Viadol NATURAL Food supplement to assist in all painful pathologies of the osteoarticular and musculotendinous system. Devils Claw The secondary roots are used for their anti-inflammatory, analgesic, and spasmodic properties due to the presence of iridoid glucosides such as procumbide and harpagoside, as well as flavones and phytosterols. The mechanism of action involves the prostaglandin and leukotrenoid system. However, it is poorly tolerated by the stomach if taken in large quantities. Glucosamine sulfate Its a nutritional treatment for osteoarthritis. Glucosamine is essential for cartilage and helps reverse osteoarticular degeneration. Chondroitin sulfate It is a molecule of complex sugars such as glycoaminoglycans and is the other constituent of cartilage. The synergistic action of glucosamine sulfate and chondroitin sulfate has been proven by various therapeutic studies, which show that using the two components together enhances their effect and reduces the dose required compared to administering either component alone. Chondroitin sulfate, in addition to regenerating cartilage, also has an anti-inflammatory effect and has shown, in various studies, to be effective against gout by helping to reduce uric acid production. It is highly effective for osteoarthritis of the hips and knees. Willow The bark of the plant is used, which contains tannins, bitter alkaloids and phenolic glucosides such as salicin, which, after hydrolysis in the body, is transformed into salicylic acid, which has anti-inflammatory, antipyretic and analgesic properties, with few side effects on the digestive system. Boswellia The plants resin is rich in triterpene soaps that release boswellic acids, which have been recognized for their strong anti-inflammatory properties, especially in rheumatoid arthritis. Boswellic acids have been shown to inhibit the activity of 5-lipoxygenase, the enzyme responsible for the synthesis of leukotrienes, important chemical mediators in joint inflammation, and have no ulcerative effects. Ash The leaves and bark are rich in tannins, polyphenols, coumarins, glucoside iridoids, as well as ash, fratin, etc. Its action is mainly as an antirheumatic, but also as a diuretic. Ingredients Devils claw dry extract 2.5% harpagoside; glucosamine sulfate; chondroitin sulfate; willow dry extract 15% salicin; boswellia dry extract 90% boswellic acids; ash dry extract 1:4; bulking agent: microcrystalline cellulose; thickener: gum arabic; anti-caking agent: magnesium stearate, micronized silica. How to use 1 ovalette 2 times a day. Warnings Pregnant or breastfeeding women and children are advised to consult their doctor. Do not exceed the recommended daily dose. Keep out of reach of children under three years of age. Supplements should not be used as a substitute for a varied diet. Format 30 900 mg ovalettes Bibliography - F. Firenzuoli: Phytotherapy. Ed. Masson - A. Bruni: General and Applied Pharmacognosy. Ed. Piccin - Gunner Samuelson: Pharmacognosy. Ed. EMSI - Brooks P. et al., Journal of rheumatology 1982 - BucciL., Nutrition report, 1996 - Drovanti a., et al. Clinical Therapeutics, 1980 - Towheed you, J Rheumatol, Nov 1999 - Pipitone V., Drugs in Experimental and clinical research, 1991