Insect repellent for the skin The effective remedy is just as suitable for tropical travel destinations (countries at risk for malaria, dengue fever and yellow fever) as for European countries. The active ingredient DEET is highly effective against mosquito bites and tick bites. Application: Apply the insect repellent evenly with the palm of your hand. To protect your facial skin, apply a small amount of the repellent to your face with your fingers. Then wash your hands and apply the repellent to the backs of your hands. To be able to eat and drink without hindrance, fingers should remain free of insect repellent. Apply insect repellent to your skin ten minutes before sun exposure during the day. If you are also using sunscreen, apply the sunscreen 30 minutes before sun exposure. Then apply the insect repellent 20 minutes later (i.e., 10 minutes before sun exposure). When the protection is no longer needed or if side effects occur, thoroughly wash the treated skin areas with soap and water.