The Nioxin System 1 amplifies hair texture and protects hair against breakage. Composition The kit includes shampoo, conditioner, and treatment that contain a combination of key ingredients, such as antioxidants and vitamins, that work synergistically to strengthen and nourish hair. Instructions for use Apply the shampoo to wet hair, gently massage the scalp, and rinse thoroughly. Then, apply the conditioner to the ends and mid-lengths of your hair and leave it on for a few minutes before rinsing. Finally, apply the treatment directly to the scalp and massage gently. No rinsing is necessary.