VICHY LIFTACTIV B3 Retinol Night Cream The LIFTACTIV B3 Retinol Anti-Pigment Spot Night Cream reduces the appearance of dark spots on the face. 4% niacinamide (vitamin B3) and 0.15% pure retinol (vitamin A) protect the skin from free radicals and stimulate skin regeneration overnight. Skin is more regenerated and radiant overnight. 98% of testers confirmed a reduced appearance of their pigment spots when using the LIFTACTIV B3 facial care routine with the LIFTACTIV B3 Serum, the LIFTACTIV B3 Anti-Pigment Spots SPF 50 Face Cream and the LIFTACTIV B3 Retinol Anti-Pigment Spots Night Face Cream. (Self-assessment by 49 women over 8 weeks.) Application : Cleanse your face thoroughly every evening. As this is a face cream containing retinol, apply the LIFTACTIV B3 Retinol Anti-Pigment Spot Night Cream twice a week during the first week. In the second week, apply it every other evening. Depending on your skins tolerance, you can incorporate the cream into your daily skincare routine starting in the third week. The retinol cream increases the skins sensitivity to light. Therefore, use a skincare product with SPF, such as the LIFTACTIV B3 Anti-Pigment Spot Cream SPF 50, the morning after application to optimally protect your skin from UV rays.