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HIGHLIGHTS Eye complex for maintaining normal vision with important vitamins, zinc, secondary plant compounds, L-glutathione and zeaxanthin Free from additives and fillers. Without magnesium stearate. Carefully manufactured in Germany on certified production lines Each batch is tested by an external laboratory for microbial contamination, heavy metals, pesticides and EtO. Ingredients and capsule shell are completely vegan INGREDIENTS PER CAPSULE Blueberry extract: 170 mg of which anthocyanidins: 17 mg Rosehip extract: 160 mg of which vitamin C: 80 mg (100% NRV) Carrot extract: 40 mg of which beta carotene: 2 mg (42% NRV) Vitamin A (Retinol Equivalents): 599 mcg (75% NRV) Total Vitamin A: 932 mcg (117% NRV) L-Glutathione: 50 mg Zinc: 10 mg (100% NRV) Vitamin E (tocopherol equivalents): 12 mg (100% NRV) Upright marigold powder: 20 mg of which lutein: 4 mg Vitamin B3 (niacin): 16.48 mg (103%) Vitamin B2 (Riboflavin): 1.4 mg (100% NRV) Vitamin B1 (Thiamine): 1.1 mg (100% NRV) Zeaxanthin: 0.1 mg Oxidative stress as a cause of many age-related eye diseases The rod cells (with photoreceptors) of our eyes consist of 65% unsaturated fatty acids (the highest percentage of all body tissues!). Unsaturated fatty acids are easily peroxidized by free radicals, meaning they are damaged by free radicals. The formation of free radicals generally occurs through oxidative stress (oxidation of O2), but in the eye especially through Photo-oxidative stress (UV light activates oxygen radicals very quickly) Antioxidants neutralize these free radicals. Antioxidant enzymes (produced in the body): Peroxidases (e.g., glutathione peroxidase, phospholipid hydroperoxide glutathione peroxidase), catalases, superoxide dismutases (SOD) Non-enzymatic antioxidants (essential = must be obtained through food): e.g., vitamins C and E, alpha-lipoic acid, secondary plant compounds such as quercetin, OPC, beta-carotene, etc. If there is an imbalance negatively affecting antioxidants, free radicals can damage the eyes. HEALTH CLAIMS REGARDING INDIVIDUAL INGREDIENTS: Vitamin A contributes to the maintenance of normal vision contributes to normal iron metabolism contributes to the maintenance of normal skin contributes to the maintenance of normal mucous membranes contributes to the normal function of the immune system has a function in cell specialization Beta-carotene contributes to the normal function of the immune system (bodys defenses). contributes to the maintenance of normal vision contributes to the maintenance of normal skin contributes to the maintenance of normal mucous membranes Vitamin B1 (Thiamine) contributes to normal psychological function contributes to normal energy metabolism contributes to normal heart function contributes to the normal function of the nervous system Vitamin B2 (Riboflavin) contributes to normal energy metabolism contributes to the normal function of the nervous system contributes to the maintenance of normal skin contributes to the maintenance of normal mucous membranes contributes to normal iron metabolism contributes to the maintenance of normal vision contributes to the maintenance of normal red blood cells contributes to the reduction of tiredness and fatigue helps protect cells from oxidative stress Vitamin B3 (Niacin) contributes to normal energy metabolism contributes to the normal function of the nervous system contributes to normal psychological function contributes to the maintenance of normal skin contributes to the maintenance of normal mucous membranes contributes to the reduction of tiredness and fatigue zinc contributes to the maintenance of normal skin contributes to normal protein synthesis contributes to the maintenance of normal testosterone levels in the blood contributes to normal carbohydrate metabolism contributes to the maintenance of normal hair contributes to the maintenance of normal nails contributes to normal macronutrient metabolism helps protect cells from oxidative stress contributes to normal fatty acid metabolism contributes to normal fertility and reproduction. contributes to normal cognitive function contributes to the normal function of the immune system (bodys defenses). contributes to the maintenance of normal bones contributes to normal acid-base metabolism contributes to the maintenance of normal vision contributes to normal vitamin A metabolism contributes to normal DNA synthesis has a function in cell division Vitamin E Vitamin E protects DNA, proteins, and lipids from oxidative damage. Vitamin C contributes to the reduction of tiredness and fatigue contributes to normal psychological function contributes to the regeneration of the reduced form of vitamin E contributes to normal energy metabolism contributes to the normal function of the immune system (bodys defenses). contributes to the normal function of the nervous system helps protect cells from oxidative stress contributes to normal collagen formation for the normal function of blood vessels. contributes to normal collagen formation for normal bone function contributes to normal collagen formation for normal cartilage function contributes to normal collagen formation for the normal function of teeth contributes to normal collagen formation for the normal function of the gums. contributes to normal collagen formation for the normal function of the skin increases iron absorption Contributes to the normal function of the immune system (bodys defense) during and after intense physical activity COMMON EYE DISEASES AND THEIR CAUSES CATARACT (GRAY CATARACT) causes Changes in lens protein structure Conversion of water-soluble proteins into cloudy, water-insoluble proteins Eye damage caused by UV radiation (especially oxidation by UV-B) Inflammation and infections (e.g., caused by cytomegalovirus) Symptoms Lens clouding, lens loss Impaired vision (“blurred vision”) Can lead to blindness Risk factors Diabetes (Diabetes increases the risk of cataracts 3-5 times! à Osmotic stress / osmotic overpressure (through diffusion of glucose + galactose into the lens) à Conversion to the sugar alcohols sorbitol + galactite Age & Predisposition (Genetics) Smoke Arteriosclerosis (including lipid peroxidation and inflammation) Light eyes Light exposure Photo-oxidative stress (e.g. solariums) Blue light (especially from computers and smartphones) stress MACULATE GENERATION Symptoms Disturbing spot in the center of the field of vision Colors become paler Cause: Degenerative processes (exact causes are still unknown); playing a central role are: Photoreceptors of the retina (especially in the macula) with high metabolic activity and high O2 consumption lead to increased radical formation. Retinal pigment epithelium (RPE) behind the retina: RPE cells dispose of oxidized (unusable) photoreceptor components through phagocytosis and removal. Disruptions of this process (oxygen deficiency, metabolic disorders, and arteriosclerosis are discussed) lead to deposits (“drusen”). which accelerate the degeneration of RPE cells and promote macular degeneration Risk factors Age & Predisposition (Genetics) Smoke Arteriosclerosis (including lipid peroxidation and inflammation) Light eyes Light exposure Photo-oxidative stress (e.g. solariums) Blue light (especially from computers and smartphones) stress GLAUCOMA (GREEN STAR) Symptoms Restriction of the visual field Blindness causes Aqueous humor drainage obstructed Increase in intraocular pressure (normal: 14-18 mm Hg) Damage and destruction of optic nerve fibers Autoimmune processes involving the formation of auto-IgG antibodies are discussed (Source: Deutsches Ärzteblatt, 3/04) Risk factors Vascular processes (e.g., arteriosclerosis) Age (> 40 years) Familial predisposition for glaucoma Nearsightedness (myopia of -5 diopters or more) Neurodegenerative processes Diabetes (see Bonovas et al.; Diabet Med 2004/21, 609-614) DIABETIC RETINOPATHY Onset: 5-30 years after the breakdown of diabetes Frequency: In cases of diabetes diagnosis: ~30% After 20 years of diabetes: ~90% Species (according to the Airlie House classification): Non-proliferative form (early form) with microaneurysms with intraretinal microhemorrhages & exudates Proliferative form (late form) with fibrovascular neoplasms, e.g., in the papilla with vitreous hemorrhages & retinal detachment Cause: Reaction of glucose and amino acids (especially lysine and arginine) → (glycosylation) Schiff bases → AGEs (advanced glycosylation end-products) AGEs are insoluble, non-reactive proteins that lead to a deterioration of oxygen supply, thickening of the retinal capillary endothelium, and ultimately to progressive capillary death. MYOPIA (SHORT SIGHT) The myopia rate is steadily increasing in the Western world. Risk factors for myopia Reduced time spent outdoors Increased use of digital media (screen activity) Increased close-up work (e.g. reading) Daylight deficit Parental smoking (especially mother during pregnancy) Pollution (e.g. particulate matter, nitrogen oxides) Poor vitamin D supply Birth and the postpartum period during seasons with high light levels increase the risk (likely leading to increased growth of the axial skeleton). (Length of the eye) Firstborn children have a higher risk Children of pregnant women over 35 have a higher risk. KEY FACTS AT A GLANCE Category: Eyes Content (grams per unit) 38.9 Content (capsules or ml per unit) 60 Ingredients: Bilberry extract, rosehip extract, coating agent (Hydroxypropylmethylcellulose), L-Glutathione, Carrot Extract, Zinc bisglycinate, DL-alpha-tocopheryl acetate, marigold powder, nicotinamide, retinyl acetate, sodium riboflavin 5-phosphate, thiamine hydrochloride, zeaxanthin. Active ingredients: lutein, zeaxanthin, anthocyanidins, vitamin C, beta-carotene, vitamins A, B1, B2, B3 and E, zinc, L-glutathione. Dosage (mg/capsule): 482. Daily intake (capsules or drops): 1. Dosage form: hard capsule. Vegan/vegetarian: vegan. Certified organic: yes. Made in (country): Germany. Storage per package (days): 60. Packaging (glass/pouch bag): glass. Category: combination products. EAN: 4260705870476. SKU: QI0040
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