Riboflavin, niacin, vitamin B6, folic acid, vitamin B12, and pantothenic acid contribute to the reduction of tiredness and fatigue. Thiamin, riboflavin, niacin, vitamin B6, vitamin B12, biotin, and pantothenic acid contribute to normal energy-yielding metabolism. Thiamin, niacin, vitamin B6, vitamin B12, and biotin contribute to the normal function of the nervous system and normal psychological function