S-adenosylmethionine (SAMe) is a naturally occurring compound that is present in all cells and is involved in the synthesis, activation, and metabolism of different molecules. Instructions for use Take 1 capsule daily between meals. Acid-resistant capsules, do not open when consuming. Ingredients S-adenosyl-L-methionine (disulfate tosylate), coating agents (hydroxypropyl methylcellulose, gum) gellan), bulking agent (cellulose), antioxidant (ascorbyl palmitate), acidity regulator (calcium oxide) Pharmaceutical advice If you are pregnant, breastfeeding, have any health problems, or are taking any medication, especially antidepressants, consult your healthcare professional before using this supplement.