Jarrow Glucosamine + Chondroitin + MSM contains vitamin C, manganese, glucosamine sulfate, chondroitin sulfate and methylsulfonylmethane (MSM). Glucosamine and chondroitin sulfate are the basic components of joint tissue involved in the production of hyaluronic acid, and it is the main component of the connective tissue of the skin. Methylsulfonylmethane (MSM) is an organic source of sulfur, a mineral antioxidant, and an important component of the bodys structural tissues such as cartilage. The sulfur in MSM is incorporated into joint tissues in the form of glycosaminoglycans (or mucopolysaccharides), such as chondroitin sulfate and hyaluronic acid. Vitamin C helps in the proper production of collagen to ensure the proper functioning of the cartilage.