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Probio-cult Akk1 Akkermansia Syxyl tablets 30 pcs The intestinal mucosa – the home of the intestinal flora. Millions of adults in Germany are aware of the importance of a healthy gut flora for metabolism, the immune system, and mental health – and already take supplements containing bacteria. Less well known, however, is that the gut flora depends on an intact intestinal lining. Continuous mucus production is the basis. The intestinal lining constantly produces mucus. This mucus forms a physical protective layer on the intestinal lining and also provides a habitat for thousands of beneficial bacteria of the gut flora. If mucus production is impaired by toxins, certain medications, or other external influences, the barrier function can decrease, as can the function of the gut flora. The intestinal mucosa can then come into direct contact with foreign substances, which can more easily penetrate the body. Conversely, a dense mucus layer allows a rich gut flora, with all its benefits, to thrive. Akkermansia muciniphila – loves the intestinal mucosa. Akkermansia muciniphila also lives in this mucus layer (muciniphila means: the mucus-loving one). Although it is one of the most common intestinal bacteria, it was only successfully isolated in 2004. In the short time since its discovery, the microorganism has already become the subject of numerous studies: Currently, research is being conducted on how a protein called “Amuc-1100” on the outer shell of Akkermansia muciniphila interacts with the mucus-producing cells of the intestinal mucosa. Akkermansia muciniphila is a strictly anaerobic bacterium, meaning it dies upon contact with oxygen in the air. A pasteurization process has now demonstrated the stability and bioavailability of the bacterium for use in a dietary supplement. to be ensured. Furthermore, this procedure increases and improves the Accessibility of the “Amuc-1100” protein. The postbiotic obtained in this way is called Pasteurized Akkermansia MucT®. Key advantages of ProBio-Cult AKK1: 1. Pasteurized Akkermansia MucT(R) does not compete with or interact with diets or supplements. Its properties are independent of added fiber or vitamins. 2. Postbiotics are more robust and less sensitive to oxygen, stomach acid, bile salts, and thus functionally reach the small and large intestines. 3. Pasteurized Akkermansia MucT(R) has been classified as safe by the European Food Safety Authority (EFSA) and approved as a Novel Food by the EU Commission. 4. ProBio-Cult AKK1 contains the same amount of Pasteurized Akkermansia MucT(R) that was used in clinical trials - 10 to 100 times more than is usually found in other bacterial products. 5. ProBio-Cult AKK1 contains a carefully selected combination of ingredients: -Methylfolate, a biologically active form of folic acid. Folate plays a role in cell division. This can be particularly important during phases of rapid growth, such as the growth of intestinal mucosal cells. -Vitamin B2 (Riboflavin): Riboflavin contributes to the maintenance of normal mucous membranes, including the intestinal mucosa. -Chamomile flower extract with apigenin: The natural flavonoid apigenin appears to interact with the gut flora. The manner in which this interaction occurs, and whether it may influence the composition and function of the gut flora, is currently the subject of research.1) ProBio-Cult Akk1 is therefore a useful addition for people who want to practice targeted intestinal care2). A healthy intestinal lining is essential! The intestinal mucosa – the home of the intestinal flora. Millions of adults in Germany are aware of the importance of a healthy gut flora for metabolism, the immune system, and mental health – and already take supplements containing bacteria. Less well known, however, is that the gut flora depends on an intact intestinal lining. Continuous mucus production is the basis. The intestinal lining constantly produces mucus. This mucus forms a physical protective layer on the intestinal lining and also provides a habitat for thousands of beneficial bacteria of the gut flora. If mucus production is impaired by toxins, certain medications, or other external influences, the barrier function can decrease, as can the function of the gut flora. The intestinal mucosa can then come into direct contact with foreign substances, which can more easily penetrate the body. Conversely, a dense mucus layer allows a rich gut flora, with all its benefits, to thrive. Akkermansia muciniphila – loves the intestinal mucosa. Akkermansia muciniphila also lives in this mucus layer (muciniphila means: the mucus-loving one). Although it is one of the most common intestinal bacteria, it was only successfully isolated in 2004. In the short time since its discovery, the microorganism has already become the subject of numerous studies: Currently, research is being conducted on how a protein called “Amuc-1100” on the outer shell of Akkermansia muciniphila interacts with the mucus-producing cells of the intestinal mucosa. Akkermansia muciniphila is a strictly anaerobic bacterium, meaning it dies upon contact with oxygen in the air. A pasteurization process has now demonstrated the stability and bioavailability of the bacterium for use in a dietary supplement. to be ensured. Furthermore, this procedure increases and improves the Accessibility of the “Amuc-1100” protein. The postbiotic obtained in this way is called Pasteurized Akkermansia MucT®. Key advantages of ProBio-Cult AKK1: 1. Pasteurized Akkermansia MucT(R) does not compete with or interact with diets or supplements. Its properties are independent of added fiber or vitamins. 2. Postbiotics are more robust and less sensitive to oxygen, stomach acid, bile salts, and thus functionally reach the small and large intestines. 3. Pasteurized Akkermansia MucT(R) has been classified as safe by the European Food Safety Authority (EFSA) and approved as a Novel Food by the EU Commission. 4. ProBio-Cult AKK1 contains the same amount of Pasteurized Akkermansia MucT(R) that was used in clinical trials - 10 to 100 times more than is usually found in other bacterial products. 5. ProBio-Cult AKK1 contains a carefully selected combination of ingredients: -Methylfolate, a biologically active form of folic acid. Folate plays a role in cell division. This can be particularly important during phases of rapid growth, such as the growth of intestinal mucosal cells. -Vitamin B2 (Riboflavin): Riboflavin contributes to the maintenance of normal mucous membranes, including the intestinal mucosa. -Chamomile flower extract with apigenin: The natural flavonoid apigenin appears to interact with the gut flora. The manner in which this interaction occurs, and whether it may influence the composition and function of the gut flora, is currently the subject of research.1) ProBio-Cult Akk1 is therefore a useful addition for people who want to practice targeted intestinal care2). A healthy intestinal lining is essential! 1) Riboflavin contributes to the maintenance of normal mucous membranes, including the intestinal mucosa. 2) Wang et al 2019 Minqian Wang, Jenni Firrman, LinShu Liu, Kit Yam, A Review on Flavonoid Apigenin: Dietary Intake, ADME, Antimicrobial Effects, and Interactions with Human Gut Microbiota, BioMed Research International, vol. 2019, Article ID 7010467, 18 pages, 2019. *Vitamin B2 (Robiflavin): contributes to the maintenance of normal mucous membranes, including the intestinal mucosa Probio-cult Duo Syxyl Capsules 100 count Designation: Dietary supplement with vitamins, glutamine and lactic acid bacteria Use/Application/Consumption Recommendation: Swallow 2 capsules whole, twice daily (morning and evening), before or with meals. Mixture of Lactobacillus acidophilus LA-5 and Bifidobacterium BB-12 Colony-forming units 1.14 x 10¹⁰ 1.14 x 10¹⁰ 2.28 x 10¹⁰ * Reference intake according to EU Regulation 1169/2011 ** No information available Ingredients: Bulking agents (cellulose, hydroxypropylmethylcellulose), amino acid L-glutamine, dextrose, lactic acid bacteria (contain milk %%% Lactobacillus acidophilus LA-5, Bifidobacterium BB-12), starch, stabilizer cellulose, anti-caking agent magnesium salts of fatty acids, color titanium dioxide, gelling agent carrageenan, thiamine mononitrate, riboflavin (vitamin B2), maltodextrin, pteroylmonoglutamic acid (folic acid), D-biotin, cholecalciferol (vitamin D3), cyanocobalamin (vitamin B12). Allergens: Milk Net fill quantity: 100 capsules = 36.3 g Storage conditions: Store in a dry place and not above 25°C. Country of origin of the food: Germany Manufacturers address: Syxyl GmbH & Co. KG Gereonsmühlengasse 5 50670 Cologne Further information: Lactose-free, gelatin-free, gluten-free and yeast-free. The stated recommended daily intake must not be exceeded. Food supplements are not a substitute for a balanced and varied diet and a healthy lifestyle. Keep out of reach of small children. Source: Information from the package insert As of November 2019
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