Medik8s unique retinyl retinoate has been shown to be 8 times more potent than retinol [1] , yet is highly tolerated by even the most sensitive skin. r-Retinoate combines vitamin A with tetrahexidecyl ascorbate, a stabilized and gentle form of vitamin C. Increasing visible skin radiance as well as providing antioxidant protection, the steps of vitamin A and C are now intertwined. *r-Retinoate Day & Night now features the equivalent level of vitamin C in C-Tetra Serum. How to use How to apply After cleansing in the morning and evening, apply r-Retinoate Day & Night evenly to your face, neck, and décolleté. Always use sunscreen in the morning while using vitamin A. r-Retinoate® Day & Night Youth Activating Day and Night Cream Aqua (Water), Tetrahexyldecyl Ascorbate, Heptyl Undecylenate, Caprylic/Capric Triglyceride, Methylpropanediol, Polylactic Acid, Cetearyl Olivate, Sodium Polyacryloyldimethyl Taurate, Cetearyl Isononanoate, Distarch Phosphate, Tocopheryl Acetate, Sorbitan Olivate, Hydrogenated Polydecene, Retinyl Retinoate, Glycerin, Caprylyl Glycol, Sodium Hyaluronate, Cholesteryl Nonanoate, Disodium EDTA, Hydroxyacetophenone, Canola Oil, Cetearyl Alcohol, Phenylpropanol, Vanilla Planifolia (Vanilla) Fruit Extract, 3-O-Ethyl Ascorbic Acid, Sodium Metabisulfite, BHT, Sodium Hydroxide, Trideceth-10.