LA La Roche-Posay Apple B3 Intensive Anti-Spot Concentrate 10% Niacinamide / Vitamin B3 30ml From loss of brightness to persistent spots: MELA B3 Serum is the new anti-spot serum with multi-patented Melasyl™ and 10% concentrated Niacinamide to correct dark spots, even persistent ones. Innovation for hyperpigmentation Melasyl™ multibreveté: the new active ingredient to fight hyperpigmentation like never before*. *Melasyl has a new unique mechanism of action: it intercepts excess melanin before it marks the skin.