Description Isdin Isdinceutics Retinal Intense Night Serum 50 ml is a night treatment formulated with retinaldehyde, designed to visibly improve skin quality. Thanks to its advanced technology, it optimizes the effectiveness of retinal while promoting better tolerance. It works overnight to help reduce the appearance of wrinkles, refine skin texture, and even out skin tone. Upon waking, the skin appears smoother, firmer and visibly brighter.