Dr. Browns pacifiers with a silicone nipple, a flexible and durable material that withstands extreme temperatures. Comes with a box to protect it from germs. Before each use, clean the box with water and mild detergent or use a soft sponge. Rinse well and dry. Benefits of the pacifier: It calms the baby and triggers the release of the hormone CCK (cholecystokinin), causing a feeling of satiety and relaxation. With a round nipple that soothes baby no matter how you place it in their mouth. With ventilation holes that allow air to pass through so that babys skin is not irritated. Reversible nipple. Made of silicone. BPA-free. Packed in sets of 2 pieces.