Dynacan Spot On Dogs 20-40 Kg 3 Pip External antiparasitic, recommended for dogs More information: DYNACAN SPOT-ON SOLUTION FOR DOGS 20-40KG QUALITATIVE AND QUANTITATIVE COMPOSITION Each 2.68 ml pipette contains: Active substances: Fipronil………………………………………………………………………………268.00 mg (S)-methoprene ........................................................................................................................................... 241.20 mg Excipients: Butylhydroxyanisole (E320) ...........................................................................................................................0.54 mg Butylhydroxytoluene (E321) ...........................................................................................................................0.27 mg For the full list of excipients, see section 6.1. PHARMACEUTICAL FORM Solution for spot-on application. Clear, colorless to slightly yellow solution. CLINICAL DATA It is a species of destination Dogs weighing 20 to 40 kg. Directions for use, specifying the target species For the treatment and prevention of flea infestations, alone or associated with ticks and/or biting lice. - Flea (Ctenocephalides spp.) elimination. Insecticidal efficacy against new infestations by Adult fleas persist for 8 weeks. Prevention of flea multiplication by inhibiting development of eggs (ovicidal activity) and of larvae and pupae (larvicidal activity) originating from eggs laid by adult fleas for eight weeks after application. - Elimination of ticks (Ixodes ricinus, Dermacentor reticulatus, Rhipicephalus sanguineus). He This veterinary medicine has an acaricidal efficacy that lasts up to 4 weeks against ticks. - Elimination of biting lice (Trichodectes canis). The veterinary medicinal product can be used as part of a treatment strategy for the control of dermatitis. Flea Allergy (FA). Contraindications In the absence of available data, this veterinary medicinal product should not be used in other animal species. In the absence of available data, the veterinary medicinal product should not be used in puppies under 8 weeks of age. of age and/or weighing less than 2 kg. Do not use on sick (e.g., systemic diseases, fever) or convalescent animals. Do not use in rabbits, as adverse drug reactions, including death, may occur. This veterinary medicine is specially developed for dogs. Do not use in cats or ferrets as This could lead to overdosing. Special warnings for each target species When applied as part of the treatment strategy for the control of allergic dermatitis to insect bites For fleas, monthly applications are recommended for the allergic animal and other dogs and cats living in the household. my house. Special precautions for use Special precautions for use in animals Weigh the animals before application. It is important to ensure that the veterinary medicine is applied to an area where the animal cannot lick it and Make sure the animals do not lick each other after treatment. Bathing or immersion in water should be avoided for 2 days following application of the veterinary medicinal product. as well as bathing more frequently than once a week, since no studies have been conducted to investigate how This affects the products effectiveness. Emollient shampoos can be used before treatment, but they reduce the protection against fleas lasts approximately 5 weeks when used weekly after from the application of the veterinary medicinal product. A weekly bath with a 2% chlorhexidine medicated shampoo does not affected the effectiveness against fleas during a 6-week study. Individual ticks may attach. For this reason, it cannot be completely ruled out. transmission of infectious diseases if conditions are unfavorable. For optimal control of flea and lice infestation in a multi-animal household, all cats and Dogs should be treated simultaneously with a suitable veterinary medicine. Pet fleas often infest the animals basket, bedding, and regular resting areas. such as carpets and soft furnishings that should be treated in case of massive infestation and at the beginning of the Control measures, using a suitable insecticide and vacuuming regularly. Do not apply the veterinary medicine to wounds or broken skin. Avoid contact with the animals eyes. In case of accidental contact with the eyes, rinse immediately with water. abundant water. Specific precautions to be taken by the person administering the veterinary medicinal product to animals This veterinary medicinal product may cause eye, skin, and mucous membrane irritation. Therefore, you should Avoid contact of the veterinary medicine with the mouth, skin and eyes. Animals or people with known hypersensitivity to insecticides or alcohol should avoid contact with this veterinary medicinal product. Avoid contact of the contents with your fingers. If this occurs, wash your hands. Wash your hands with soap and water. After accidental eye exposure, rinse the eye thoroughly with clean water. If eye irritation persists If symptoms persist, seek medical attention immediately and show the package insert or label to the doctor. Wash your hands with soap and water after applying the veterinary medicine. Treated animals should not be touched until the application site is dry, and should not be allowed to Children should not play with treated animals until the application site is dry. Therefore, it is recommended not to treat them. the animals during the day, but rather at dusk, and that these recently treated animals do not sleep with the owners, especially with the children. Do not smoke, drink or eat during application. Animals or people with known hypersensitivity to fipronil or to the excipients (see section 6.1) should Avoid all contact with the veterinary medicine. Other precautions Dogs should not be allowed to swim in streams or ponds for 2 days following application (see section 6.6). Adverse reactions (frequency and severity) Very rare adverse reactions reported after use include: skin reactions transient effects at the application site (skin discoloration, local hair loss, itching, redness), as well as General itching or hair loss. Excessive salivation has been observed very rarely after use. reversible nervous system changes (increased sensitivity to stimulation, depression, other nervous system signs), vomiting, or respiratory symptoms. In cases of licking, a brief period of excessive salivation may be observed on very rare occasions due to mainly due to the nature of the excipient. The frequency of adverse reactions should be classified according to the following groups: - Very frequently (more than 1 animal out of every 10 treated animals shows adverse reactions) - Frequently (more than 1 but less than 10 animals per 100 animals treated) - Infrequently (more than 1 but less than 10 animals per 1,000 animals treated) - Rarely (more than 1 but less than 10 animals per 10,000 animals treated) - Very rarely (less than 1 animal per 10,000 animals treated, including isolated cases). Use during pregnancy, breastfeeding or laying The veterinary medicine can be used during pregnancy and lactation. Interaction with other medications and other forms of interaction None known. Dosage and route of administration Solution for spot-on application. Dosage: - One 2.68 ml pipette per dog weighing more than 20 kg and up to 40 kg. This corresponds to a minimum recommended dose of 6.7 mg/kg of fipronil and 6 mg/kg of (S)-methoprene. A monthly application is recommended when there is a high risk of reinfestation, if the dog is allergic to the flea bites, or in situations where tick control is required. In the absence of safety studies, the minimum treatment interval is 4 weeks. Method of administration: Hold the pipette upright. Tap the narrow end of the pipette to ensure the contents are dispensed. It remains inside the main body of the pipette. Detach the tip. Part the animals fur along the At the base of the neck, in front of the shoulder blades, until the skin is visible. Place the tip of the pipette on the skin and squeeze. pipette several times until its contents are completely emptied directly onto the skin at a single point. When applying the veterinary medicine to the skin, avoid excessively wetting the coat, as the treated area It may appear wet or greasy after application. If this occurs, it will disappear within 24 hours. hours after the application. Overdosage (symptoms, emergency measures, antidotes), if necessary No adverse reactions have been observed in safety studies conducted in the target species, in puppies. Eight-week-old, growing dogs weighing approximately 2 kg were treated once to five times a day. Recommended dose. The risk of experiencing adverse reactions (see section 4.6) may still be increased. when overdosed, so animals should always be treated with the pipette size appropriate to their weight bodily. Itching may occur after application. Waiting time(s) Not applicable. PHARMACOLOGICAL PROPERTIES The veterinary medicinal product is an insecticidal and acaricidal solution for topical use containing a combination of an adulticidal active ingredient, fipronil, in combination with an ovicidal and larvicidal active ingredient, (S) - methoprene. Pharmacotherapeutic group: topical ectoparasiticides QP53