Formula enhanced with innovative ingredients and technologies: RetinSphere® Technology , a combination of retinoids that prevents pore occlusion, helping to reduce the formation and development of whiteheads and blackheads; glycolic and salicylic acids, which intensify exfoliating and keratolytic activity; BIOPEP-15 , which reduces the proliferation of microorganisms; niacinamide, which helps improve the appearance of imperfections and, thanks to its depigmenting activity, prevents and/or improves spots caused by acne. Apply once a day to clean, dry skin. RetinSphere® Technology. BIOPEP-15. Salicylic acid. Glycolic acid. Niacinamide.