Atopivet Collar is the first and only product for supporting the epidermal barrier with a delayed effect of up to 2 months. It is a dermatological product for large and very large dogs, which helps maintain the integrity of healthy skin while nourishing and repairing it. It is waterproof and does not require removal during bathing. The black color of the collar helps protect the active substance. The main ingredient, BIOSFEEN, is a unique sphingolipid extract, developed by Bioiberica, which has ceramides and a high content of sphingomyelin, a precursor of ceramides. Biosfeen increases ceramide levels naturally, stimulating their endogenous synthesis. Thus, this easy-to-use collar protects and repairs the skin, moisturizes it and helps to relieve symptoms of excessive scratching. Benefits: The first and only product to support the epidermal barrier with a delayed effect of up to 2 months. BIOSFEEN as the main ingredient - a unique sphingolipid extract, which has ceramides and a high content of sphingomyelin, a precursor of ceramides; thus Biosfeen increases ceramide levels naturally, stimulating their endogenous synthesis Helps maintain skin integrity; Helps relieve itching (excessive scratching). Repairs the skin barrier and hydrates the skin. Protects the skin for 2 months. It is waterproof and does not require removal during bathing. It can be used together with other products. Atopivet collar Medium & Large Dogs is recommended for dogs over 4 months of age and weighing over 10 kg. It is effective for 2 months.