Cleanance Comedomed Concentrate reduces blemishes and blackheads in just seven days*. Thanks to the unique mode of action of Comedoclastin™, a plant-based active ingredient with patented properties**, it combats blemishes at their source, targeting microcomedones and guaranteeing anti-recurrence action***. Tested on over 4,600 people and prescribed by dermatologists****, Cleanance Comedomed Concentrate is the expert care solution for all acne-prone skin types in adolescents aged 12 and over and adults (including pregnant women). Apply twice a day (morning and evening) to the face, trunk and back. Its light, non-greasy texture leaves the skin with a matte finish. *Clinical score, twice a day on the face, 51 subjects. **Patent pending. ***Used twice a day on the face, it helps limit the recurrence of blemishes. Efficacy demonstrated over 8 weeks, 37 subjects. ****IQVIA - Xponent PharmaOne - acne market (83A1A) in French pharmacies - 2021 - volume and value. Composition AVENE THERMAL WATER (AVENE AQUA). ISOPROPYL ALCOHOL. PEG-6. GLYCERIN. SILYBUM MARIANUM FRUIT EXTRACT. SILICA. POLYACRYLATE-13. POLYISOBUTHENE. POLYSORBATE 20. SORBITAN ISOSTEARATE. WATER (AQUA) Instructions for use Comedomed can be used alone, in combination with other acne medications or after a medical treatment. It can be applied to the clean face, trunk and back, morning and evening. Expert tip: Keep a short but essential routine! - 1 deep facial cleansing or make-up removal: morning and evening! - 1 anti-blemish treatment, also morning and evening. ingredients AVENE THERMAL WATER (AVENE AQUA). ISOPROPYL ALCOHOL. PEG-6. GLYCERIN. SILYBUM MARIANUM FRUIT EXTRACT. SILICA. POLYACRYLATE-13. POLYISOBUTHENE. POLYSORBATE 20. SORBITAN ISOSTEARATE. WATER (AQUA) Pharmaceutical advice 3 times a day. There are no precautions for use. Avoid contact with eyes.