Arthrovet HA 60 tablets, Vetexpert Arthrovet HA 60 tablets – a preparation for dogs and cats that supports the joints The innovative composition of Arthrovet HA has been developed for dogs and cats with abnormalities of joints and cartilage. The product also supports the balanced growth of young animals. The formula is based on chemical compounds whose positive effect on the joints has been scientifically proven. Glucosamine hydrochloride, chondroitin sulfate and sodium hyaluronate improve cartilage elasticity and significantly reduce your dogs pain. Vitamin C helps in the formation of extracellular matrix proteins in the articular cartilage, thus improving the functioning of animals affected by osteoarthritis. Even if your pet does not show problems with joint function, it is worth administering half of the daily dose of the product as a preventive measure. This provides more effective protection for stressed limbs and prevents injuries. The convenient tablets are available in practical packaging, ensuring precise and hygienic dosing of the product. INDICATIONS ArthroVet HA is a supporting preparation for dogs and cats with impaired articular cartilage and joint function. It is recommended both for young animals during a period of intensive growth and for older animals with osteoarthritis. COMPOSITIONmineralsADDITIVESglucosamine hydrochloridechondroitin sulfatesodium hyaluronateVitamin C 25DOSAGE It is recommended to administer 1 tablet per 20 kg body weight. Prophylactically: half of the daily dose. MECHANISM OF ACTION The mechanism of action of the dietary supplement ArthroVet HA is based on the effects of the individual ingredients of this preparation, as described in the scientific literature: The preparation contains three main components of glycosaminoglycans (GAG) of the extracellular matrix of articular cartilage, namely glucosamine, chondroitin (in the form of sulfate) and hyaluronic acid. Increasing their intake in the animals diet may improve the synthesis of endogenous GAG (glucosamine) and increase the water content in the articular cartilage (chondroitin and hyaluronic acid), which improves its elasticity. The beneficial effects of glucosamine and chondroitin sulfate in dogs with osteoarthritis have been confirmed in randomized, double-blind clinical studies (osteoarthritis) conducted by McCarthy et al. (2007). In these studies, dogs that received glucosamine and chondroitin sulfate showed clinically significant improvements in pain indices, weight-bearing on limbs and severity of the disease. ArthroVet HA is also one of the first products on the market containing hyaluronic acid, which is absorbed after oral administration (Balogh et al., 2008), and the use of a mixture of glucosamine, chondroitin and hyaluronic acid ensures greater efficacy of the preparation than the use of a preparation containing only glucosamine and chondroitin in the treatment of patients with degenerative changes in the knee joint (Bucci et al., 2005). Vitamin C supports the production of extracellular matrix proteins in the articular cartilage and acts as a coenzyme in collagen synthesis. Ascorbic acid (vitamin C) is a coenzyme for prolyl and lysyl hydroxylases, which are key enzymes in collagen synthesis. In in vitro studies, ascorbate and ascorbic acid increased the synthesis of proteins and proteoglycans by articular cartilage chondrocytes (Ameye and Chee, 2006). As a result, the complementary feed ArthroVet HA contains active substances with a scientifically proven mechanism of supporting joints in patients with osteoarthritis. Presentation: 60 tablets