The uniqueness with the standardized extract AS 195 offers a natural solution. The beneficial ingredients of Antistax® are natural substances known as flavonoids, which come from red grape leaf extract (Vitis vinifera). Flavonoids cannot be produced by the body and must be obtained through diet. Numerous clinical studies have shown that natural flavonoids help maintain good venous circulation. They have also been shown to protect blood vessels by stabilizing their walls and increasing their elasticity. The result of these actions is the maintenance of good venous circulation, the reduction of the appearance of edema (swollen legs) and the improvement of unpleasant symptoms, such as the sensation of heaviness and pain. Antistax® contains a unique standardized extract of natural flavonoids, AS 195, which has been used for decades to maintain good functioning of the veins of the lower limbs. It is produced under the strictest specifications and ensures the same qualitative and quantitative composition of beneficial ingredients in each tablet from all batches. It is available and used in Germany, France, Italy and many other countries. Antistax® Cooling Leg Gel contains 1,250 mg AS 195 extract/100 g.